Proposition C passed by almost a 3-1 ratio as Show Me State residents voted to exempt Missouri from the insurance mandate in the new health care law.
Sen. Jane Cunningham, a Republican who was one of the prime sponsors of the measure, lauded the vote afterwards.
"The citizens of the Show-Me State don't want Washington involved in their health care decisions," she said, according to the St. Louis Post-Dispatch. "I've never seen anything like it. Citizens wanted their voices to be heard."
Missouri was the first of four states seeking to opt out of the insurance purchase mandate portion of the health care law Obama pushed and the vote on Tuesday could prompt others to move forward.